Before IVF: Preparing Your Body and Mind for Treatment
- Sabrina Houtrique
- Nov 6
- 4 min read
Embarking on in vitro fertilisation (IVF) can be both hopeful and overwhelming. Many people find that preparing physically and emotionally before starting IVF may help them feel more organised and supported. It’s not just about medical readiness — it’s about feeling grounded and supported through what can be a deeply personal journey.
Below are some key areas many people explore with their fertility specialist before beginning treatment.
1. Autoimmune & Inflammatory Health
Your immune system plays an important role in early pregnancy. In some people, underlying immune conditions or chronic inflammation may influence fertility or embryo implantation. Some clinicians may suggest autoimmune screening, especially in cases of unexplained infertility or recurrent miscarriage.
For those with MTHFR gene variations, understanding how your body processes folate and B vitamins can help guide preconception nutrition. Supporting your body with the right nutrients can make a difference — but always under guidance from your healthcare provider.
2. Allo-Immunity & Genetic Compatibility
In some couples, the immune system may identify the partner’s genetics as unfamiliar, which could influence embryo implantation. Tests such as DQ Alpha genotyping or other immune compatibility assessments may be explored in cases of failed implantation or miscarriage.
These results are usually reviewed alongside other medical factors to guide treatment planning. It’s one of many tools your fertility specialist may consider.
Please note: These tests are not routinely recommended for everyone and do not predict IVF outcomes; your specialist will advise if they’re appropriate in your situation.
3. Natural Killer (NK) Cells & KIR Typing
Some fertility clinics explore the activity of certain immune cells, including natural killer (NK) cells, which are involved in early pregnancy. Overactive or imbalanced immune responses may be associated with implantation issues in some people.
If appropriate, your clinician might discuss simple supportive strategies such as correcting low Vitamin D, omega-3 intake, and managing stress. These steps aim to support healthy immune balance.
4. Vaginal Microbiome & Reproductive Health
The vaginal microbiome — the community of protective bacteria in the vagina — plays a key role in fertility and implantation. If you’re planning IVF, your provider may suggest a vaginal microbiome swab to assess for imbalances or overgrowths.
If needed, they may recommend a targeted plan to help restore microbiota balance using probiotics and other therapies. This kind of testing helps create a healthier environment for embryo transfer.
5. Egg & Sperm Quality
Healthy reproductive cells are the foundation of IVF. For women, ovarian reserve testing (e.g., AMH blood tests or follicle scans) provides insight into egg quantity. For men, semen analysis can assess sperm count, motility, and structure.
Improving reproductive cell quality is often a 3-month process. Your specialist may suggest antioxidant-rich nutrition, lifestyle changes, or preconception supplements to support general wellbeing.
6. Whole-Body Wellness
Your overall health matters. The lead-up to IVF is a good time to gently support your body with simple daily practices:
Aim for a healthy, stable weight
Minimise alcohol and quit smoking if applicable
Prioritise good sleep hygiene
Stay active with low-impact movement
Consider counselling, acupuncture, or mindfulness
These habits may help reduce stress and support overall wellbeing. It’s okay to take it one step at a time — consistency is key.
IVF Readiness at a Glance
Focus Area | What It May Include |
Immune Health | Autoimmune screening, inflammation review, MTHFR support |
Immune Compatibility | DQ Alpha genotyping, allo-immune balance assessment |
Immune Regulation | NK cell/KIR testing, gentle nutrient/lifestyle support |
Vaginal Microbiome | Testing and probiotic/antibiotic plans (if needed) |
Reproductive Cells | Egg/sperm health optimisation, 3-month prep plans |
General Wellness | Nutrition, sleep, movement, stress reduction |
Final Thoughts
Preparing for IVF is about more than lab results — it’s about feeling empowered and informed. The journey can be challenging, but taking steps to care for your body, mind, and environment may help you feel more confident and supported.
If you’re considering IVF or planning your first cycle, it’s okay to ask questions and explore your options. Many people find reassurance in knowing they’ve taken proactive steps — with the guidance of their healthcare team — to prepare for what lies ahead.
Contact Us
The Infusion Centre
📍 306 Olsen Avenue, Parkwood QLD 4214
📞 +61 449 916 829
External sources: Your IVF Australia – RANZCOG Consumer Guidance
Disclaimer: This article is general education only and is not medical advice. It does not recommend specific tests or treatments for any individual, and it does not guarantee improved fertility or IVF success. Any investigations or therapies mentioned are considered by your treating specialist based on your history and clinical findings. We do not advertise prescription-only medicines or biologicals to the public, and we do not promote or facilitate access to these products. If such therapies are relevant, they are discussed privately between patients and their doctors. All information provided by The Infusion Centre is intended for general education and wellness support only. Our services do not replace medical advice, diagnosis, or treatment from your doctor or specialist. Always consult your healthcare provider—particularly if you are pregnant, breastfeeding, taking medication, or managing a health condition—before commencing any treatment. Individual outcomes may vary. Clinical guidance and suitability vary by person; pre-conception care is individualised and determined in consultation with your clinician. 
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